Computational Biology

All biology is computational biology

Here, I argue that computational thinking and techniques are so central to the quest of understanding life that today all biology is computational biology. Computational biology brings order into our understanding of life, it makes biological concepts rigorous and testable, and it provides a reference map that holds together individual insights. The next modern synthesis in biology will be driv...

Computational Biology

A pair in a string is the occurrence of the same substring twice. A pair is maximal if the two occurrences of the substring cannot be extended to the left and right without making them different. The gap of a pair is the number of characters between the two occurrences of the substring. In this paper we present methods for finding all maximal pairs under various constraints on the gap. In a str...

Computational Biology

2. Computational Genomics and Proteomics . . . . . . . . . . . . . . . . 3 2.1. DNA Sequencing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.2. DNA and RNA Structures . . . . . . . . . . . . . . . . . . . . . . 3 2.3. Protein Sequencing . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.4. Protein Structure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.5. ...

Computational Molecular Biology

Computational biology for ageing

High-throughput genomic and proteomic technologies have generated a wealth of publicly available data on ageing. Easy access to these data, and their computational analysis, is of great importance in order to pinpoint the causes and effects of ageing. Here, we provide a description of the existing databases and computational tools on ageing that are available for researchers. We also describe t...